Bardoxolone methyl (other names “RTA 402” and “CDDO-methyl ester”) is a synthetic oleananetriterpenoid that is an orally-available first-in-class antioxidant inflammation modulator (AIM). It is the most potent known inducer of the Keap1-Nrf2pathway to enter clinical development and works to suppress both oxidative stress and inflammation.
The...
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